Job Description
Note: The job is a remote job and is open to candidates in USA. RefinedScience is dedicated to advancing care by integrating science and data to uncover pathways to better health. They are seeking a Computational Biologist II to perform bioinformatics analyses, collaborate with teams, and contribute to research initiatives using established methods on evolving datasets.
- Responsibilities
- Execute bioinformatics and computational biology analyses with guidance from project and team leads
- Collaborate effectively with bioinformatics colleagues, cross-functional teams, and external partners
- Apply established methods to new and evolving datasets
- Document analyses using reproducible research practices
- Contribute to scientific reports and presentations
- Participate in code reviews and team knowledge-sharing
- Continuously learn new tools and approaches to support high-quality, scalable research and analytics initiatives at RefinedScience
- Skills
- PhD in bioinformatics, computational biology, molecular biology, genomics, biostatistics, computer science, or related quantitative discipline (OR Master's with 2+ years relevant experience)
- Proficiency in R or Python for data analysis and visualization
- Familiarity with Linux/Unix command-line environments
- Proficiency with Git/GitHub
- Experience working with large-scale biological datasets
- Exposure to conda, Docker, or similar tools
- Training in and/or demonstrated ability to analyze and extract biological insights from single-cell datasets (e.g., scRNA-seq, ATAC-seq, CITE-seq, or other multi-omics data)
- Understanding of next-generation sequencing technologies and data processing workflows
- Solid understanding of statistical methods for biological data analysis (hypothesis testing, differential expression, dimensionality reduction, clustering, etc.)
- Strong understanding of molecular biology principles; familiarity with cancer biology, immunology, hematology, or other relevant disease areas
- Demonstrated independent research through doctoral thesis work
- Author or co-author on peer-reviewed publications (submitted or published)
- Experience presenting research findings at lab meetings, seminars, or conferences
- Proven ability to formulate research questions, design analytical approaches, and troubleshoot complex data analysis challenges
- Experience with single-cell analysis frameworks (Seurat, scverse, Bioconductor packages)
- Familiarity with applying AI/ML methods and tools to computational biology tasks
- Familiarity with pandas, numpy, scikit-learn, or similar libraries commonly used for data science and scientific computing
- Exposure to cloud computing platforms (GCP)
- Understanding of experimental design for genomics studies
- Strong project and time management skills
- Excellent written and verbal communication skills
- Collaborative mindset and willingness to share knowledge and support team members
- Prior experience working in Biotech or Pharma environment
- Company Overview
- RefinedScience uses data, technology, and expertise to accelerate drug development. It was founded in 2019, and is headquartered in Aurora, Colorado, USA, with a workforce of 11-50 employees. Its website is https://www.refinedscience.com/.
- Company H1B Sponsorship
- RefinedScience has a track record of offering H1B sponsorships, with 1 in 2025, 1 in 2023. Please note that this does not guarantee sponsorship for this specific role.
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