Job Description
Scismic is supporting the growth of a fast-growing biotech startup focusing on animal genomics. They are seeking a Bioinformatics Scientist to transform raw sequencing data into high-impact biological insights.
- What You’ll Do
- Pipeline Architecture: Build and manage end-to-end WGS and low-pass sequencing pipelines (QC, alignment, variant calling, and annotation).
- Genomic Dataset Development: Construct and refine species-specific genotype datasets, starting with equine and expanding across multiple large animal models.
- Statistical Analysis: Lead association studies (GWAS) and population genetics analyses to identify actionable genetic targets.
- Reproducible Science: Maintain scalable, containerized workflows using Nextflow or Snakemake within cloud environments.
- Predictive Modeling: Develop custom ML/AI frameworks to support trait modeling, animal valuation, and performance forecasting.
- Who You Are
- Technical Expert: Strong background in NGS data analysis, specifically whole-genome sequencing (WGS) and variant discovery.
- Coder: Proficient in Python and/or R, with deep comfort in Linux, HPC, or cloud computing (AWS/GCP).
- Workflow Driven: Experience using Docker and workflow languages (WDL/Nextflow) to ensure reproducible results.
- Analytically Minded: You enjoy the challenge of imputation, polygenic risk scores (PRS), and translating complex data into clear recommendations.
- Preferred Experience
- Direct experience in large animal genomics (equine, bovine, or porcine).
- Background in population genetics or agricultural genomics.
- Familiarity with building data products in a startup or rapid-growth setting.
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